Evaluation of Deltamethrin in Combination of Piperonyl Butoxide (PBO) against Pyrethroid Resistant, Malaria Vector, Anopheles stephensi in IRS Implementation: an Experimental Semi-Filed Trial in Iran
نویسندگان
چکیده
Background The aim of this study was to evaluate different concentrations of deltamethrin combined with formulated piperonyl butoxide (PBO) synergist on various surfaces against the wild strain of Anopheles stephensi, the main malaria vector in Southern Iran under semi-field condition. Methods Four concentrations of deltamethrin WG 25% (Tagros) and PBO 800EC-UV (Endura) were prepared and sprayed on the pre-designed surfaces in accordance with WHO alliance line of the IRS Micronair®. The WHO's recommended bioassay kit and method was used during this study. Results Comparing the mortality rate of mosquitoes, the results showed a significant difference between months after treatment of IRS (Indoor Residual Spraying) (P< 0.05) but didn't show any significant differences between days during the first and second months (P> 0.05).Statistical test revealed a significance difference between mortality rate of mosquitoes in exposing to concentrations of 1 and 4 (P< 0.05) which demonstrated effect of synergizing PBO on mortality rate. Conclusion This research as the first semi-field trial on deltamethrin added to different concentrations of formulated PBO for IRS, indicates that deltamethrin+10X PBO is more effective than other concentrations. Therefore, using synergists can be suggested as a new tool for prevention of pyrethriod resistance, although more studies are recommended.
منابع مشابه
Susceptibility Status of Anopheles Stephensi Liston the Main Malaria Vector, to Deltamethrin and Bacillus Thuringiensis in the Endemic Malarious Area of Hormozgan Province, Southern Iran
Background & Aims: Anopheles stephensi is one of the most important malaria vectors in Hormozgan province, southern Iran. This species with high density has an effective role in malaria transmission, especially in plain and coastal areas. At present, the country malaria vector control program in areas with local transmission is using deltamethrin 5% and Bacillus thuringiensis as insecticide ...
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